Generics (Harvoni | Sovaldi | Hepcinat)

Use of generic versions of direct-acting antivirals resulted in very high cure rates for people who obtained the products through three buyers’ clubs, indicating that the generic products are effective.

Hepatitis C

Hepatitis C is a serious viral disease that can lead to cirrhosis or liver cancer. Only treatment with high-quality and proven medicines will help stop the spread of the virus. Some of the most effective drugs are Harvoni, Copegus, Sovaldi, Daklinza, Rebetol. They managed to prove themselves from the best side. Numerous customer reviews and recommendations of doctors speak about the productivity of drugs.

Hepatitis C is a viral liver disease. The disease passes without visible symptoms, and the infected person may not be aware of the infection. In the future, there is a possibility of cirrhosis or liver cancer.

According to unofficial data, more than 150,000,000 people are infected in the world, and half a million die every year. With the help of the latest development of drugs to combat viral disease, it is possible to cure up to 95 % of infected people.

How are they infected?

Infection occurs "due" to the effect of the virus on human blood. It can occur due to the use of a non-sterile medical instrument, repeated use after use by a patient with Hepatitis C, or intravenous drug use with a non-sterile medical instrument.

The virus is also transmitted sexually with an infected partner, from an infected mother to an infant. However, these types of virus transmission are less common.

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Hepatitis C cannot be transmitted through breastfeeding, water, safe sexual contact, or kissing. If you are near an infected person and spend time together with them, eat food, etc.there is no risk of infection.

The geography of the virus

The virus is most commonly found in third world African countries, the Asian Eastern region, and the European Eastern Mediterranean region. In USA at the moment, according to official data, 4.5 million people are infected with hepatitis C (Million Americans Living with Hepatitis C). However, the true figure is higher because not everyone knows that they are ill.

Complications of the disease

The older a person is, the more difficult the disease is for them, and the virus develops faster. Drinking alcohol can complicate the condition of an infected person, as it adversely affects the liver.

Symptom of disease

The incubation period of the disease is from 14 days to one and a half months. After the virus enters the body, 4/5 of people do not notice changes in the body. The remaining 20 % may have a fever, loss of appetite, yellowing of the skin, constant fatigue.

Disease prevention

Primary

Exclusion of the possibility of illness in medical institutions.

Secondary

For the population, as a preventive measure, it is necessary to:

  • Hepatitis a and B vaccination;
  • condom use;
  • healthy lifestyle.

Highest risk groups

This includes the following groups of people:

  • intravenous drug users;
  • mother-to-child transmission;
  • having piercings and tattoos;
  • HIV-infected people;
  • Have unprotected sexual relations with a sick person.

Treatment of hepatitis C

Previously, there were no methods for treating the viral disease hepatitis C. Now, thanks to the innovative developments of leading organizations for the production of medicines, this opportunity has appeared.

According to official data, one million patients were able to start treatment in 2015. A year later, 2.9 million people had this opportunity. The goal is to reach the treatment level of 80% of infected people by 2030.

Generic Hepatitis C Drugs

There are several effective medicines for the treatment of Hepatitis C, which have high ratings from specialists, as well as numerous positive reviews from patients.

Copegus

It is an antiviral drug. Created and produced by the Swiss company F. Hoffmann-La Roche.

The main active component of the drug is ribavirin. It is effective in the treatment of other viral diseases, such as HIV infection.

It is used in combination with interferon-alpha. This combination increases the effectiveness of treatment by 3 times.

Ingredients: ribavirin, starch, hypromellose, cellulose, etc.

Taken orally. Medications after the end of the course are released after 2-3 weeks, which gives you the effect of the drug for a long time.

You can buy Copegus by prescription. Consult your doctor before use.

It can not be used for allergies to certain components, heart diseases, thyroid, kidney failure, blood poisoning, during pregnancy, breast-feeding. During the use of the drug, you must completely stop drinking alcohol.

During the use of the drug, it is necessary to exclude the possibility of conception, since it can harm the fetus. Before starting the treatment course, you must do a pregnancy test. The drug can harm the seminal fluid, so during the use of the drug, men also need to refrain from the possibility of fertilization of their partner.

Experts recommend using two contraceptives at the same time to exclude the possibility of pregnancy by 100 %. For example, a condom and pills.

During treatment, you must take a monthly pregnancy test. If the result is positive, the treatment is stopped.

The dosage is calculated based on the patient's weight. It is applied twice a day.

  • If the weight is less than 65 kg. 4 tablets (2 and 2);
  • From 65 to 105 kg 5 tablets (2 and 3);
  • If the weight is more than 105 kg, 6 tablets.

The duration of the course depends on the course of the disease and the person's reactions to the drug. The course can take from 4 months to six months. In some cases, it may take longer.

In case of overdose, gastric lavage is necessary. You can't change the dosage yourself. Follow the schedule in the application.

It has some side effects:

  • Rash;
  • migraines;
  • Violation of the menstrual cycle;
  • Weakness;
  • Hearing loss, etc.

Shelf life is 48 months. Acceptable storage temperatures are from + 5 to +30 degrees.

It is one of the top ten best-selling medicines. Numerous studies in USA and around the world have shown the effectiveness of the drug after the first applications together with interferon-alpha.

Sovaldi

Medication for hepatitis C. It is produced based on the active substance sofosbuvir by the American company Gilead. It suppresses the growth of the virus at the DNA level.

In the early 2010s, studies of this drug were conducted in the United States and Israel, involving more than 2000 infected people. After 3 months of Sovaldi's use, almost 100 % of infected patients were completely cured.

This drug is a real breakthrough in the fight against hepatitis C because it has the highest effectiveness, almost 100 percent positive result, and almost no side effects.

1 tablet contains 400 mg of sofosbuvir. Another substances-magnesium stearate, cellulose, etc. The tablet is labeled 7977 and GSI.

The duration of treatment depends on the genotype of the viral disease. It is used for 1 tablet a day. The tablet must be swallowed, not chewed or crushed.

Sovaldi is used in conjunction with ribavirin. Or with interferon-alpha in combination with ribavirin.

Among the contraindications: an allergic reaction to the components of the substance.

Among the side effects: cough, shortness of breath, insomnia, nausea, decreased hemoglobin, constipation, rash.

Shelf life is 24 months. Store in a dry, inaccessible place at a temperature no higher than 30 degrees.

It ranks first among the best-selling medicines in the United States. Actress and model Pamella Anderson after 16 years of fighting hepatitis C, which she contracted in 2002 after getting a tattoo with a non-sterile needle, was able to fully recover.

Harvoni

The drug is designed for the treatment of hepatitis C. the Active substances are sofosbuvir and ledipasvir. It is the first drug that allows you to completely recover from a viral disease without the use of interferon and ribavirin.

Harvoni after 3 months of use, in the course of the research, gave 95 percent positive results.

Consult your doctor before use. You can not purchase the drug without a doctor's prescription. It is used for the treatment of hepatitis C with genotype 1 and 4.

Take one tablet a day

.

Side effects include headache and fatigue. When using Harvoni, it is not prohibited to drive a car. However, if a person feels tired, it is not recommended to get behind the wheel.

Complex use of drugs together with Harvoni is not required since their active substances affect sofosbuvir. Similarly, it acts on other active substances.

Rebetol

The active substance of the drug is ribavirin. One capsule contains 200 mg. The composition includes cellulose, lactose, magnesium stearate. It should be used in combination with interferon-alpha increases the activity of the substance.

It is effective in the treatment of HIV infection.

Rebetol cannot be used for:

  • Allergies;
  • Breast-feeding the baby;
  • Pregnancies;
  • Severe heart disease;
  • Renal failure.

During application, it is necessary to exclude the possibility of fertilization. When undergoing treatment in a man, it is necessary to exclude the possibility of pregnancy of a sexual partner. Doctors recommend using 2 contraceptives at the same time.

The dosage is prescribed by your doctor and depends on your body weight. It is applied twice a day.

  • If the weight is less than 65 kg, 4 capsules (2 and 2);
  • From 65 to 85 kg 5 capsules (2 and 3);
  • 86-100 kg 6 capsules;
  • 106 and higher 7 capsules (3 and 4).

Rebetol can be taken by children. If the weight is less than 25 kg, it is used as a syrup.

Side effects: migraine, decreased hemoglobin, menstrual disorders, depression, vomiting, diarrhea, etc.

You can only purchase the drug with a prescription from your doctor. Shelf life is 24 months. Storage temperature up to 30 degrees.

Daklinza

A drug with the active substance of declare war dihydrochloride. Auxiliary: magnesium stearate, cellulose, silicon dioxide, etc.

It is available in pentagonal tablets with BMS and 213 or 215 engravings (different dosages of the active substance are 30 and 60 mg).

It is used in conjunction with other medications.

Daklinza is not prescribed for allergies to the active substance, during pregnancy, during lactation, to persons who have not reached the age of majority.

The daily required dosage is 60 mg. The duration of treatment of the course is from 3 months to six months, depending on the genotype of the viral disease.

Consult your doctor before use.

There may be side effects on Daklinza and medications used in combination. Possible headache, fatigue, diarrhea, decreased appetite, rash, abdominal pain.

The drug is available on prescription. Shelf life 24 months, store in a dry place inaccessible to children at a temperature of up to 30 degrees.

Beware of fakes

There are all sorts of fakes for these medicines, which do not help to fight hepatitis C and harm the body. If you have the opportunity to buy drugs from this list at a low price-do not agree. Perhaps they are trying to deceive you. Do not become victims of scams.

Conclusion

Hepatitis C is not a verdict. Modern medicine has made a step forward, many drugs have been developed that effectively fight viral diseases. The best drugs, Sovaldi, Harvoni, Copegus, etc., will give you the joy of life and confidence in the future. Only proven medicines can eliminate the virus 100 %.

By: Dr. Jimmy Nguyen, DO

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